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Article

Molecular mimicry and immunomodulation by the HRES-1 endogenous retrovirus in SLE

1 Jan 2008

Abstract excerpt

Genetic and environmental factors are believed to influence development of systemic lupus erythematosus (SLE). Endogenous retroviruses (ERV) correspond to the integrated proviral form of infectious retroviruses, which are trapped within the genome due to mutations. ERV represent a key molecular link between the host genome and infectious viral particles. ERV-encoded proteins are recognized by antiviral immune...

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PMID: 18432409
DOI: 10.1080/08916930802024764

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