Article
Genetic and functional association of FAM5C with myocardial infarction.
BMC medical genetics - 22 Apr 2008
Connelly Jessica J, Shah Svati H, Doss Jennifer F, Gadson Shera, Nelson Sarah, Crosslin David R, Hale A Brent, Lou Xuemei, Wang Ty, Haynes Carol, Seo David, Crossman David C, Mooser Vincent, Granger Christopher B, Jones Christopher J H, Kraus William E, Hauser Elizabeth R, Gregory Simon G
Abstract excerpt
BACKGROUND: We previously identified a 40 Mb region of linkage on chromosome 1q in our early onset coronary artery disease (CAD) genome-wide linkage scan (GENECARD) with modest evidence for linkage (n = 420, LOD 0.95). When the data are stratified by acute coronary syndrome (ACS), this modest maximum in the overall group became a well-defined LOD peak (maximum LOD of 2.17, D1S1589/D1S518). This peak overlaps a...
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