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Article

Variation in the bone morphogenetic protein-2 gene: effects on fat and lean body mass in young and elderly women.

European journal of endocrinology - 1 May 2008

McGuigan Fiona, Larzenius Emma, Callreus Mattias, Gerdhem Paul, Luthman Holger, Akesson Kristina

Abstract excerpt

OBJECTIVE: Bone morphogenetic protein-2 (BMP2) plays a critical role in osteoblastogenesis and adipogenesis from osteoprogenitor cells. The balance between osteogenic and adipogenic effects is influenced by BMP2 concentration, transcription factors and age. BMP2 single nucleotide polymorphisms (SNPs) may contribute to osteoporosis risk, but the relationship between adiposity and body composition has not been...

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Source

Identifiers

PMID: 18426824
DOI: 10.1530/EJE-07-0757

Genes

BMP2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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