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Article

A structural model of the GDP dissociation inhibitor rab membrane extraction mechanism.

The Journal of biological chemistry - 27 Jun 2008

Ignatev Alexander, Kravchenko Sergey, Rak Alexey, Goody Roger S, Pylypenko Olena

Abstract excerpt

Rab GDP dissociation inhibitors (GDI)-facilitated extraction of prenylated Rab proteins from membranes plays an important role in vesicular membrane trafficking. The investigated thermodynamic properties of yeast Rab.GDI and Rab.MRS6 complexes demonstrated differences in the Rab binding properties of the closely related Rab GDI and MRS6 proteins, consistent with their functional diversity. The importance of the...

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PMID: 18426803
DOI: 10.1074/jbc.M709718200

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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