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Adenovirus Virion Stability and the Viral Genome: Size Matters

30 Sept 2009

Abstract excerpt

Ongoing investigations into the fundamental aspects of virus biology continue to provide crucial insights for the development of more effective virus-based therapeutics. Within the field of gene therapy, these discoveries have translated into virus vectors with improved tissue tropism, prolonged transgene expression, and enhanced safety. However, radical modifications to the viral genome or capsid constituents...

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PMID: 19789561
DOI: 10.1038/mt.2009.202

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