Article
Molecular heterogeneity of calcium channel beta-subunits in canine and human heart: evidence for differential subcellular localization.
Physiological genomics - 13 Apr 2004
Foell Jason D, Balijepalli Ravi C, Delisle Brian P, Yunker Anne Marie R, Robia Seth L, Walker Jeffrey W, McEnery Maureen W, January Craig T, Kamp Timothy J
Abstract excerpt
Multiple Ca2+ channel beta-subunit (Ca(v)beta) isoforms are known to differentially regulate the functional properties and membrane trafficking of high-voltage-activated Ca2+ channels, but the precise isoform expression pattern of Ca(v)beta subunits in ventricular muscle has not been fully characterized. Using sequence data from the Human Genome Project to define the intron/exon structure of the four known...
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