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Article

Scalable efficient expansion of mesenchymal stem cells in xeno free media using commercially available reagents.

Journal of translational medicine - 17 Jul 2015

Riordan Neil H, Madrigal Marialaura, Reneau Jason, de Cupeiro Kathya, Jiménez Natalia, Ruiz Sergio, Sanchez Nelsy, Ichim Thomas E, Silva Francisco, Patel Amit N

Abstract excerpt

BACKGROUND: The rapid clinical translation of mesenchymal stem cells (MSC) has resulted in the development of cell-based strategies for multiple indications. Unfortunately one major barrier to widespread implementation of MSC-based therapies is the limited supply of fetal calf serum (FCS) used to expand cells to therapeutic numbers. Additionally, the xenogeneic element of fetal calf serum has been previously...

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Source

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Identifiers

PMID: 26183703
DOI: 10.1186/s12967-015-0561-6
PMCID: PMC4504159

Genes

MSC

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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