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Article

The subcellular localization of TRPP2 modulates its function.

Journal of the American Society of Nephrology : JASN - 1 Jul 2008

Fu Xiao, Wang Yan, Schetle Nelli, Gao Hongyu, Pütz Michael, von Gersdorff Gero, Walz Gerd, Kramer-Zucker Albrecht G

Abstract excerpt

TRPP2, also known as polycystin-2, is a calcium permeable nonselective cation channel that is mutated in autosomal dominant polycystic kidney disease but has also been implicated in the regulation of cardiac development, renal tubular differentiation, and left-to-right (L-R) axis determination. For obtaining further insight into how TRPP2 exerts tissue-specific functions, this study took advantage of...

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Identifiers

PMID: 18417723
DOI: 10.1681/ASN.2007070730
PMCID: PMC2440294

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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