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Article

hTERT mediates gastric cancer metastasis partially through the indirect targeting of ITGB1 by microRNA-29a

23 Feb 2016

Abstract excerpt

Human telomerase reverse transcriptase (hTERT) plays a key role in tumor invasion and metastasis, but the mechanism of its involvement in these processes is not clear. The purpose of this study is to investigate the possible molecular mechanism of hTERT in the promotion of gastric cancer (GC) metastasis. We found that the up-regulation of hTERT in gastric cancer cells could inhibit the expression of miR-29a and...

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PMID: 26903137
DOI: 10.1038/srep21955

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