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Article

Stress-dependent changes in the properties of p53 complexes by the alternative translation product p53/47

1 Apr 2008

Abstract excerpt

P53 plays a key role in the cellular response to damage exposure and in preventing the development of human cancers. Activation of p53 results in changes in the expression of a large number of gene products. However, relatively little is still known how p53 activation differentiates between different types of damages in different types of tissues or how this triggers either an apoptotic response or cell cycle...

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Identifiers

PMID: 18414054
DOI: 10.4161/cc.7.7.5626

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