Article
The power and robustness of maximum LOD score statistics.
Annals of human genetics - 1 Jul 2008
Yoo Y J, Mendell N R
Abstract excerpt
The maximum LOD score statistic is extremely powerful for gene mapping when calculated using the correct genetic parameter value. When the mode of genetic transmission is unknown, the maximum of the LOD scores obtained using several genetic parameter values is reported. This latter statistic requires higher critical value than the maximum LOD score statistic calculated from a single genetic parameter value. In...
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