Percentiles of the null distribution of 2 maximum lod score tests.

Abstract excerpt

We here consider the null distribution of the maximum lod score (LOD-M) obtained upon maximizing over transmission model parameters (penetrance values, dominance, and allele frequency) as well as the recombination fraction. Also considered is the lod score maximized over a fixed choice of genetic model parameters and recombination-fraction values set prior to the analysis (MMLS) as proposed by Hodge et al. The...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Genetic Linkage
• Share to Likelihood Functions
• Share to Linkage Disequilibrium