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Article

Breast cancer resistance protein (ABCG2) and drug disposition: intestinal expression, polymorphisms and sulfasalazine as an in vivo probe.

Pharmacogenetics and genomics - 1 May 2008

Urquhart Bradley L, Ware Joseph A, Tirona Rommel G, Ho Richard H, Leake Brenda F, Schwarz Ute I, Zaher Hani, Palandra Joe, Gregor Jamie C, Dresser George K, Kim Richard B

Abstract excerpt

Breast cancer resistance protein (BCRP) is an efflux transporter expressed in tissues that act as barriers to drug entry. Given that single nucleotide polymorphisms (SNPs) in the ABCG2 gene encoding BCRP are common, the possibility exists that these genetic variants may be a determinant of interindividual variability in drug response. The objective of this study is to confirm the human BCRP-mediated transport of...

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Share to ATP Binding Cassette Transporter, Subfamily G, Member 2
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 18408567
DOI: 10.1097/FPC.0b013e3282f974dc
PMCID: PMC4043148

Genes

ABCG2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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