Article
Polymorphisms of the ICAM-1 gene are associated with biliary atresia.
Digestive diseases and sciences - 1 Jul 2008
Arikan Cigdem, Berdeli Afig, Kilic Murat, Tumgor Gokhan, Yagci Rasit V, Aydogdu Sema
Abstract excerpt
UNLABELLED: Inflammation is an important feature of biliary atresia, and recent studies suggest that its occurs in a genetically susceptible host. The intercellular adhesion molecule-1 (ICAM-1) is of paramount importance for the initiation and propagation of various inflammatory conditions. AIM: To determine whether the Glu241Arg polymorphism in the ICAM-1 gene, which impairs inflammatory responses, is associated...
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