Analysis of the functional relevance of a putative regulatory SNP of PDCD1, PD1.3, associated with systemic lupus erythematosus.

doi:10.1038/gene.2008.19

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Article

Analysis of the functional relevance of a putative regulatory SNP of PDCD1, PD1.3, associated with systemic lupus erythematosus.

Genes and immunity - 1 Jun 2008

Suarez-Gestal M, Ferreiros-Vidal I, Ortiz J A, Gomez-Reino J J, Gonzalez A

Abstract excerpt

This study aimed to test the functional effects of the PD1.3 single nucleotide polymorphism (SNP) (rs11568821), which were proposed based on its association to systemic lupus erythematosus (SLE) susceptibility and in electrophoretic mobility shift assays (EMSA) results. We analysed transcriptional effects of the PD1.3 locus by enhancer reporter assays. Results were against the hypothesis that the PD1.3 locus acts...

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Identifiers

PMID: 18401354
DOI: 10.1038/gene.2008.19

Genes

PDCD1
RUNX1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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