Article
Association of PDCD1 with susceptibility to systemic lupus erythematosus: evidence of population-specific effects.
Arthritis and rheumatism - 1 Aug 2004
Ferreiros-Vidal Isabel, Gomez-Reino Juan J, Barros Francisco, Carracedo Angel, Carreira Patricia, Gonzalez-Escribano Francisca, Liz Myriam, Martin Javier, Ordi Josep, Vicario Jose L, Gonzalez Antonio
Abstract excerpt
OBJECTIVE: The A allele of the PD1.3 single-nucleotide polymorphism (SNP) on the programmed cell death gene PDCD1 was markedly more frequent in patients with systemic lupus erythematosus (SLE) than in unaffected controls in a recent study involving large sets of Swedish, European American, and Mexican families. This study sought to determine the role of PDCD1 in susceptibility to SLE in the Spanish population....
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