Article
Ecotropic Viral Integration Site 5 (EVI5) variants are associated with multiple sclerosis in Iranian population.
Multiple sclerosis and related disorders - 1 Nov 2017
Mazdeh Mehrdokht, Ghafouri-Fard Soudeh, Noroozi Rezvan, Sayad Arezou, Khani Maryam, Taheri Mohammad, Davood Omrani Mir
Abstract excerpt
BACKGROUND: Multiple sclerosis (MS) is a multifactorial disorder with immunological basis. Numerous genetic and environmental factors contribute in its pathogenesis. Several genetic loci have been shown to be associated with MS risk. Among genes whose participation in MS has been evaluated is Ecotropic Viral Integration Site 5 (EVI5). EVI5 is a common site of retroviral integration with a possible role in T-cell...
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