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Article

Enrichment of oligodendrocyte precursor phenotypes in subsets of low-grade glioneuronal tumours

1 Jan 2024

Abstract excerpt

Current histological classification of low-grade glioneuronal tumours does not adequately represent their underlying biology. The neural lineage(s) and differentiation stage(s) involved and the cell state(s) affected by the recurrent genomic alterations are unclear. Here, we describe dysregulated oligodendrocyte lineage developmental programmes in three low-grade glioneuronal tumour subtypes. Ten dysembryoplastic...

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PMID: 38764775
DOI: 10.1093/braincomms/fcae156

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