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Article

Influence of the cystathionine beta-synthase 844ins68 and methylenetetrahydrofolate reductase 677C>T polymorphisms on folate and homocysteine concentrations.

European journal of human genetics : EJHG - 1 Aug 2008

Summers Carolyn M, Hammons Andrea L, Mitchell Laura E, Woodside Jayne V, Yarnell John W G, Young Ian S, Evans Alun, Whitehead Alexander S

Abstract excerpt

A high homocysteine, low folate phenotype is a feature of many diseases. The effect of the cystathionine beta-synthase (CBS) 844ins68 polymorphism on homocysteine and folate concentrations was examined alone and in the context of the 5,10-methylenetetrahydrofolate reductase (MTHFR) 677C>T polymorphism in a Northwestern European male population. The MTHFR 677TT genotype is known to be associated with increased...

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Share to Cystathionine beta-Synthase
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Methylenetetrahydrofolate Reductase (NADPH2)

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Share to Polymerase Chain Reaction

Share to Polymorphism, Genetic

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Source

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Identifiers

PMID: 18398434
DOI: 10.1038/ejhg.2008.69
PMCID: PMC4051220

Genes

MTHFR
CBS

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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