Article
Enumeration of functionally active anti-Aspergillus T-cells in human peripheral blood.
Journal of immunological methods - 1 Jun 2008
Beck Olaf, Koehl Ulrike, Tramsen Lars, Mousset Sabine, Latgé Jean Paul, Müller Katrin, Schwabe Dirk, Bader Peter, Klingebiel Thomas, Lehrnbecher Thomas
Abstract excerpt
Invasive aspergillosis remains a life-threatening complication in patients undergoing allogeneic stem cell transplantation (SCT). Since CD4(+) T-cells provide a critical secondary defense against Aspergillus spp., the quantification of "functional" anti-Aspergillus T-cells might be important in the clinical care of allogeneic transplant patients. We present a rapid, simple and reproducible method to enumerate...
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