Expression pattern diversity and functional conservation between retroposed PRAT genes from Drosophila melanogaster and Drosophila virilis.

Abstract excerpt

Gene duplication by retrotransposition duplicates only the coding and untranslated regions of a gene and, thus, biases retroduplicated genes toward having different expression patterns from their parental genes. As such, genes duplicated by retrotransposition are more likely to develop novel expression domains. To explore this idea further, we used the Prat/Prat2 gene duplication in Drosophila as a case study to...

Topics

• Amidophosphoribosyltransferase
• Animals
• Drosophila
• Drosophila Proteins
• Drosophila melanogaster
• Female
• Gene Duplication
• Gene Expression Profiling
• Gene Expression Regulation, Developmental
• Gonads
• Green Fluorescent Proteins
• Male
• Microscopy, Fluorescence
• Models, Genetic