Article
Significance of Arg3, Arg54, and Tyr58 of L-aspartate α-decarboxylase from Corynebacterium glutamicum in the process of self-cleavage.
Biotechnology letters - 1 Jan 2014
Cui Wenjing, Shi Zengxiu, Fang Yueqin, Zhou Li, Ding Ning, Zhou Zhemin
Abstract excerpt
PURPOSE OF WORK: We have elucidated the significance of three key amino acid residues of L-aspartate α-decarboxylase that act remotely from its cleavage site for its functional self-cleavage as well as for its catalytic activity. These results provide useful fundamental information for engineering L-aspartate α-decarboxylase. L-Aspartate α-decarboxylase (ADC) from Corynebacterium glutamicum, and encoded by panD,...
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