Article
Role of the somatostatin system in contextual fear memory and hippocampal synaptic plasticity.
Learning & memory (Cold Spring Harbor, N.Y.) - 1 Apr 2008
Kluge Christian, Stoppel Christian, Szinyei Csaba, Stork Oliver, Pape Hans-Christian
Abstract excerpt
Somatostatin has been implicated in various cognitive and emotional functions, but its precise role is still poorly understood. Here, we have made use of mice with somatostatin deficiency, based upon genetic invalidation or pharmacologically induced depletion, and Pavlovian fear conditioning in order to address the contribution of the somatostatin system to associative fear memory. The results demonstrate an...
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