Article

Generalization of contextual fear is sex-specifically affected by high salt intake

2022-09-22

Abstract excerpt

A hallmark symptom of many anxiety disorders, and multiple neuropsychiatric disorders more broadly, is generalization of fearful responses to non-fearful stimuli. Anxiety disorders are often comorbid with cardiovascular diseases. One established, and modifiable, risk factor for cardiovascular diseases is salt intake. Yet, investigations into how excess salt consumption affects anxiety-relevant behaviors remains li...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 4e678dad-72cb-55ca-9558-a6c5620967ba
DOI: 10.1101/2022.09.20.508397

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Generalization of contextual fear is sex-specifically affected by high salt intakeDOI 10.1101/2022.09.20.508397Read

Female WMI rats with genetic stress hyper-reactivity show enhanced contextual fear memory without deficit in extinction of fearSemantic proximity Read

High threat intensity increases conditioned fear generalization and makes extinction of a generalization stimulus less effectiveSemantic proximity Read

Towards new approaches to disorders of fear and anxiety.Semantic proximity Read

The role of hippocampal spatial representations in contextualization and generalization of fearSemantic proximity Read

A Meta-Analysis of Conditioned Fear Generalization in Anxiety-Related DisordersSemantic proximity Read

Sugar Beverage Habitation Relieves Chronic Stress-Induced Anxiety-like Behavior but Elicits Compulsive Eating Phenotype via vLSGAD2 Neurons.Semantic proximity Read

Genotype determining aerobic exercise capacity associates with behavioral plasticity in middle-aged rats.Semantic proximity Read

Chronic salt-loading reduces basal excitatory input to CRH neurons in the paraventricular nucleus and accelerates recovery from restraint stress in male mice.Semantic proximity Read

Behavioral and genetic architecture of fear conditioning and related phenotypes.Semantic proximity Read

Early life stress in male mice blunts responsiveness in a translationally-relevant reward taskSemantic proximity Read

Fear-conditioning to unpredictable threats reveals sex differences in rat fear-potentiated startle (FPS)Semantic proximity Read

Species-relevant inescapable stress differently influences memory consolidation and retrieval of mice in a spatial radial arm maze.Semantic proximity Read