Article
Low rate of emergence of nevirapine and lamivudine resistance after post-partum interruption of a triple-drug regimen.
Antiviral therapy - 1 Jan 2008
Pérez Héctor, Vignoles Moira, Laufer Natalia, Gómez Alejandro, Coll Patricia, Lottner Jorge, Rolón María, Salomón Horacio, Cahn Pedro
Abstract excerpt
INTRODUCTION: Emergence of nevirapine (NVP) resistance may be a consequence of its use in monotherapy to prevent HIV mother-to-child transmission (MTCT). The aim of this study was to evaluate the emergence of strains resistant to NVP and lamivudine (3TC) after discontinuation of antiretroviral therapy (ART) with 3TC/zidovudine (ZDV)/NVP. METHODS: Twenty pregnant women (ART-naive or preexposed only to ZDV), to...
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