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Article

Quinolone-resistant gyrase mutants demonstrate decreased susceptibility to triclosan.

The Journal of antimicrobial chemotherapy - 1 Oct 2017

Webber Mark A, Buckner Michelle M C, Redgrave Liam S, Ifill Gyles, Mitchenall Lesley A, Webb Carly, Iddles Robyn, Maxwell Anthony, Piddock Laura J V

Abstract excerpt

Objectives: Cross-resistance between antibiotics and biocides is a potentially important driver of MDR. A relationship between susceptibility of Salmonella to quinolones and triclosan has been observed. This study aimed to: (i) investigate the mechanism underpinning this; (ii) determine whether the phenotype is conserved in Escherichia coli; and (iii) evaluate the potential for triclosan to select for quinolone...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 29091182
DOI: 10.1093/jac/dkx201

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

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