Article
The RGS gene loco is essential for male reproductive system differentiation in Drosophila melanogaster.
BMC developmental biology - 3 Apr 2008
McGurk Leeanne, Pathirana Stephen, Rothwell Kathleen, Trimbuch Thorsten, Colombini Paolo, Yu Fengwei, Chia William, Bownes Mary
Abstract excerpt
BACKGROUND: The loco gene encodes several different isoforms of a regulator of G-protein signalling. These different isoforms of LOCO are part of a pathway enabling cells to respond to external signals. LOCO is known to be required at various developmental stages including neuroblast division, glial cell formation and oogenesis. Less is known about LOCO and its involvement in male development therefore to gain...
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