Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Cytological and Transcript Analyses Reveal Fat and Lazy Persister-Like Bacilli in Tuberculous Sputum

26 Mar 2008

Abstract excerpt

BACKGROUND: Tuberculous sputum provides a sample of bacilli that must be eliminated by chemotherapy and that may go on to transmit infection. A preliminary observation that Mycobacterium tuberculosis cells contain triacylglycerol lipid bodies in sputum, but not when growing in vitro, led us to investigate the extent of this phenomenon and its physiological basis. METHODS AND FINDINGS: Microscopy-positive sputum...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Infectious Diseases and Tuberculosis
Share to Mycobacterium research and diagnosis
Share to Tuberculosis Research and Epidemiology

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 18384229
DOI: 10.1371/journal.pmed.0050075

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Cytological and Transcript Analyses Reveal Fat and Lazy Persister-Like Bacilli in Tuberculous SputumPMID 18384229Read ↗

Non-Replicating Mycobacterium tuberculosis Elicits a Reduced Infectivity Profile with Corresponding Modifications to the Cell Wall and Extracellular MatrixSemantic proximity Read ↗

Acid-Fast Positive and Acid-Fast NegativeMycobacterium tuberculosis: The Koch ParadoxSemantic proximity Read ↗

Potassium availability triggers Mycobacterium tuberculosis transition to, and resuscitation from, non-culturable (dormant) states.Semantic proximity Read ↗

Experimental Models of Foamy Macrophages and Approaches for Dissecting the Mechanisms of Lipid Accumulation and Consumption during Dormancy and Reactivation of TuberculosisSemantic proximity Read ↗

Dual-Reporter Mycobacteriophages (Φ 2 DRMs) Reveal Preexisting Mycobacterium tuberculosis Persistent Cells in Human SputumSemantic proximity Read ↗

Characterization of Drug-Resistant Lipid-Dependent Differentially Detectable Mycobacterium tuberculosisSemantic proximity Read ↗

Flow cytometry method for absolute counting and single-cell phenotyping of mycobacteriaSemantic proximity Read ↗

A novel in vitro multiple-stress dormancy model for Mycobacterium tuberculosis generates a lipid-loaded, drug-tolerant, dormant pathogen.Semantic proximity Read ↗

Intrabacterial lipid inclusions in mycobacteria: unexpected key players in survival and pathogenesis?Semantic proximity Read ↗

Triacylglycerols: Fuelling the Hibernating Mycobacterium tuberculosisSemantic proximity Read ↗

Beyond culturability: VBNC-like and differentially culturable Mycobacterium tuberculosis challenge growth-based interpretations of bacterial viability.Semantic proximity Read ↗

Nitrogen deprivation induces triacylglycerol accumulation, drug tolerance and hypervirulence in mycobacteriaSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.