Article
Association of interleukin-23 receptor variants with ankylosing spondylitis.
Arthritis and rheumatism - 1 Apr 2008
Rahman Proton, Inman Robert D, Gladman Dafna D, Reeve Jeff P, Peddle Lynette, Maksymowych Walter P
Abstract excerpt
OBJECTIVE: Recent studies have shown that a nonsynonymous single-nucleotide polymorphism (SNP) (Arg381Gln; rs11209026) in the interleukin-23 receptor (IL-23R) gene on chromosome 1p31 is associated with Crohn's disease and psoriasis. Given the clinical and immunologic overlap between ankylosing spondylitis (AS) and these diseases, and the potential function of this candidate SNP, this study was undertaken to...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
