Article
ARLTS1 - a novel tumor suppressor gene.
Cancer letters - 8 Jun 2008
Yendamuri Sai, Trapasso Francesco, Calin George A
Abstract excerpt
ARLTS1 (ADP-ribosylation factor-like tumor suppressor gene 1) is a member of the ARF family of the Ras superfamily of small GTPases that are known to be involved in multiple regulatory pathways altered in human carcinogenesis. Here, we review recent work that has provided insights into the role of this small gene as an emerging player in both familial and sporadic cancers of several histotypes. ARLTS1 is a low...
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