Article
Borrelia burgdorferi membranes are the primary targets of reactive oxygen species.
Molecular microbiology - 1 May 2008
Boylan Julie A, Lawrence Kevin A, Downey Jennifer S, Gherardini Frank C
Abstract excerpt
Spirochetes living in an oxygen-rich environment or when challenged by host immune cells are exposed to reactive oxygen species (ROS). These species can harm/destroy cysteinyl residues, iron-sulphur clusters, DNA and polyunsaturated lipids, leading to inhibition of growth or cell death. Because Borrelia burgdorferi contains no intracellular iron, DNA is most likely not a major target for ROS via Fenton reaction....
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