Article
Dissection of the antiviral NK cell response by MCMV mutants.
Methods in molecular biology (Clifton, N.J.) - 1 Jan 2008
Jonjic Stipan, Krmpotic Astrid, Arapovic Jurica, Koszinowski Ulrich H
Abstract excerpt
Our understanding of virus control by natural killer (NK) cells relies mainly on in vitro observations. The significance of these findings for virus control in vivo is not yet fully understood. Complexity is added by the fact that many viruses, particularly herpesviruses, are equipped with sets of genes that, dependent on the genetic background of the host, modify the NK cell response. The advent of recombinant...
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