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Article

Leukocyte tyrosine kinase functions in pigment cell development.

PLoS genetics - 7 Mar 2008

Lopes Susana S, Yang Xueyan, Müller Jeanette, Carney Thomas J, McAdow Anthony R, Rauch Gerd-Jörg, Jacoby Arie S, Hurst Laurence D, Delfino-Machín Mariana, Haffter Pascal, Geisler Robert, Johnson Stephen L, Ward Andrew, Kelsh Robert N

Abstract excerpt

A fundamental problem in developmental biology concerns how multipotent precursors choose specific fates. Neural crest cells (NCCs) are multipotent, yet the mechanisms driving specific fate choices remain incompletely understood. Sox10 is required for specification of neural cells and melanocytes from NCCs. Like sox10 mutants, zebrafish shady mutants lack iridophores; we have proposed that sox10 and shady are...

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Identifiers

PMID: 18369445
DOI: 10.1371/journal.pgen.1000026
PMCID: PMC2265441

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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