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Article

Nucleotide frequency variation across human genes.

Genome research - 1 Dec 2003

Louie Elizabeth, Ott Jurg, Majewski Jacek

Abstract excerpt

The frequencies of individual nucleotides exhibit significant fluctuations across eukaryotic genes. In this paper, we investigate nucleotide variation across an averaged representation of all known human genes. Such a representation allows us to average out random fluctuations that constitute noise and uncover remarkable systematic trends in nucleotide distributions, particularly near boundaries between genetic...

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PMID: 14613976
DOI: 10.1101/gr.1317703
PMCID: PMC403801

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