Article
Histamine metabolism influences blood vessel branching in zebrafish reg6 mutants.
BMC developmental biology - 25 Mar 2008
Huang Cheng-chen, Huang Chin-Wei, Cheng Yih-Shyun E, Yu John
Abstract excerpt
BACKGROUND: Vascular branching morphogenesis is responsible for the extension of blood vessels into growing tissues, a process crucial for organogenesis. However, the genetic mechanism for vessel branching is largely unknown. Zebrafish reg6 is a temperature-sensitive mutation exhibiting defects in blood vessel branching which results in the formation of swollen vessel lumina during capillary plexus formation....
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