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Article

Physical inactivity interacts with an endothelial lipase polymorphism to modulate high density lipoprotein cholesterol in the GOLDN study.

Atherosclerosis - 1 Oct 2009

Smith Caren E, Arnett Donna K, Tsai Michael Y, Lai Chao-Qiang, Parnell Laurence D, Shen Jian, Laclaustra Martin, Junyent Mireia, Ordovás José M

Abstract excerpt

BACKGROUND: Plasma high density lipoprotein (HDL) cholesterol (HDL-C) concentration is highly heritable but is also modifiable by environmental factors including physical activity. HDL-C response to exercise varies among individuals, and this variability may be associated with genetic polymorphisms in the key regulators of HDL metabolism including endothelial lipase (LIPG). METHODS: We examined associations...

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Topics

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Share to Polymorphism, Single Nucleotide

Source

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Identifiers

PMID: 19380136
DOI: 10.1016/j.atherosclerosis.2009.03.012
PMCID: PMC2801595

Genes

LIPG

Variants

rs2000813

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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