Article
Quantitative detection of circulating endothelial cells in vasculitis: comparison of flow cytometry and immunomagnetic bead extraction.
Journal of thrombosis and haemostasis : JTH - 1 Jun 2008
Clarke L A, Shah V, Arrigoni F, Eleftheriou D, Hong Y, Halcox J, Klein N, Brogan P A
Abstract excerpt
BACKGROUND: Circulating endothelial cells (CECs) are biomarkers for endothelial cell (EC) injury and are quantified using immunomagnetic bead extraction (IBE), or flow cytometry (FC). Reports suggest that there is good agreement between these methods for CEC quantification. OBJECTIVES: We examined levels of agreement between these techniques in children with systemic vasculitis. METHODS: We added HUVEC or human...
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