Article
A new approach for rapid and reliable enumeration of circulating endothelial cells in patients.
Journal of thrombosis and haemostasis : JTH - 1 May 2012
Kraan J, Strijbos M H, Sieuwerts A M, Foekens J A, den Bakker M A, Verhoef C, Sleijfer S, Gratama J W
Abstract excerpt
BACKGROUND: Mature circulating endothelial cells (CECs) are surrogate markers of endothelial damage/dysfunction. A lack of standardized assays and consensus on CEC phenotype has resulted in a wide variation of reported CEC numbers (4-1300 per mL). OBJECTIVES: Given the need for a quick, reliable, robust and validated CEC assay at an affordable price, we present a novel approach to enumerate CECs using a...
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