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Article

Isotype controls in phenotyping and quantification of microparticles: a major source of error and how to evade it.

Thrombosis research - 1 Jan 2008

Trummer Arne, De Rop Christiane, Tiede Andreas, Ganser Arnold, Eisert Roswith

Abstract excerpt

BACKGROUND: The characterisation and quantification of cell-derived microparticles (MPs) using flow cytometry are often complicated by a low staining intensity and a non-discrete signal pattern of many cell surface antigens. Fluorescence-labelled isotype controls (ICs) are commonly used to set limits for the discrimination of antigen positive vs. negative events. OBJECTIVES: The influence of different ICs on the...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 18304614
DOI: 10.1016/j.thromres.2008.01.005

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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