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Article

Genetic markers of tumour necrosis factor alpha in aggressive and chronic periodontitis.

Journal of clinical periodontology - 1 Jun 2008

Schulz Susanne, Machulla Helmut K G, Altermann Wolfgang, Klapproth Jana, Zimmermann Uta, Gläser Christiane, Kluttig Alexander, Stein Jamal, Schaller Hans-Günter, Reichert Stefan

Abstract excerpt

AIM: Tumour necrosis factor alpha (TNFalpha) plays an important role in the pathogenesis of periodontitis. TNFalpha production is influenced by gene polymorphisms. The aim of this study was to evaluate links between genetic variants and chronic/aggressive periodontitis in a multivariate model. SUBJECTS: One hundred and twenty-three periodontitis patients (chronic: n=54, aggressive: n=69) and 52 healthy controls...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 18363738
DOI: 10.1111/j.1600-051X.2008.01226.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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