Article
The del/del genotype of the nuclear factor-kappaB -94ATTG polymorphism and its relation to aggressive periodontitis.
Journal of periodontal research - 1 Jun 2010
Schulz S, Hierse L, Altermann W, Klapproth J, Zimmermann U, Reichert Y, Gläser C, Kluttig A, Stein J M, Schaller H-G, Reichert S
Abstract excerpt
BACKGROUND AND OBJECTIVE: Periodontitis is influenced by specific host-dependent immune responses. Periodontopathogens induce innate immune responses, amongst others, via toll-like receptor 2 (TLR2), resulting in activation of the nuclear transcription factor nuclear factor-kappaB (NF-kappaB). The aim of this case-control study was to evaluate links between genetic variants of these genes and chronic/aggressive...
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