A case-control study of promoter and 5'UTR VEGF polymorphisms in diabetic retinopathy.

doi:10.5507/bp.2025.032

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Article

A case-control study of promoter and 5'UTR VEGF polymorphisms in diabetic retinopathy.

Biomedical papers of the Medical Faculty of the University Palacky, Olomouc, Czechoslovakia - 1 Sept 2026

Abu-Hassan Diala Walid, Al-Bdour Muawyah D, Tahir Huda, Freihat Mona, Saleh Ibraheem, El-Khateeb Mohammed, Kelley Mary J

Abstract excerpt

AIMS: Angiogenesis is activated in the retina of diabetic patients with retinopathy complications. Vascular endothelial growth factor (VEGF) plays an essential role as a mediator of the retinal induced neovascularization. VEGF levels are increased significantly in the vitreous and aqueous ocular fluids in the patients with proliferative diabetic retinopathy. The aim of this study is to investigate whether VEGF...

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Topics

Humans
Diabetic Retinopathy
Female
Male
Case-Control Studies
Vascular Endothelial Growth Factor A

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Promoter Regions, Genetic

Middle Aged

Diabetes Mellitus, Type 2

5' Untranslated Regions

Polymorphism, Genetic

Genotype

Genetic Predisposition to Disease

Aged

Source

Open in PubMed

Identifiers

PMID: 41410038
DOI: 10.5507/bp.2025.032

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 25 Oct 2026.

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