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Article

Genotype-phenotype correlations for exudative age-related macular degeneration associated with homozygous HTRA1 and CFH genotypes.

Investigative ophthalmology & visual science - 1 Jul 2008

Leveziel Nicolas, Zerbib Jennyfer, Richard Florence, Querques Giuseppe, Morineau Gilles, Fremeaux-Bacchi Veronique, Coscas Gabriel, Soubrane Gisèle, Benlian Pascale, Souied Eric H

Abstract excerpt

PURPOSE: Major genetic factors for age-related macular degeneration (AMD) have recently been identified as susceptibility risk factors, including polymorphisms of HTRA1 and CFH genes. The purpose was to analyze the angiographic features of patients harboring homozygous genotypes for HTRA1 and CFH genes in a French exudative AMD population. METHODS: Two hundred patients affected with exudative AMD were genotyped...

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Source

Identifiers

PMID: 18362109
DOI: 10.1167/iovs.07-1540

Genes

CFH
HTRA1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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