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Article

Genotype-phenotype associations in neovascular age-related macular degeneration.

Retina (Philadelphia, Pa.) - 1 Oct 2012

Hogg Ruth E, McKay Gareth J, Hughes Anne E, Muldrew Katherine A, Chakravarthy Usha

Abstract excerpt

PURPOSE: To examine associations between recognized genetic susceptibility loci and angiographic subphenotypes of the neovascular variant of age-related macular degeneration (nvAMD). METHODS: Participants (247 nvAMD, 52 early age-related macular degeneration [AMD], and 103 controls) were genotyped (complement factor H and ARMS2/HTRA1). nvAMD participants were assigned to one of two subcategories: mainly classic...

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Identifiers

PMID: 22487577
DOI: 10.1097/IAE.0b013e31824dadf1

Genes

ARMS2
HTRA1

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