Article
Expression of endothelial intercellular adhesion molecule-1 is determined by genotype: effects on efficiency of leukocyte adhesion to human endothelial cells.
Human immunology - 1 Feb 2008
Holder Angela L, Wolf Sabine, Walshe Claire, Pandya Priti, Stanford Rachel E, Smith John D, Rose Marlene L, Lawson Charlotte
Abstract excerpt
Two biallelic polymorphisms, previously described in the human intercellular adhesion molecule (ICAM)-1 gene at codon 241 (glycine [G] to arginine [R] substitution) and codon 469 (glutamic acid [E] to lysine [K] substitution) have been associated with a number of diseases including myocardial infarction, transplant rejection, and diabetes. However, the functional significance of these polymorphisms has not been...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
