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Article

C/T polymorphism of the intercellular adhesion molecule-1 gene (exon 6, codon 469). A risk factor for coronary heart disease and myocardial infarction.

International journal of cardiology - 1 Aug 2002

Jiang Hong, Klein Rolf Michael, Niederacher Dieter, Du Ming, Marx Roger, Horlitz Mark, Boerrigter Guido, Lapp Harald, Scheffold Thomas, Krakau Ingo, Gülker Hartmut

Abstract excerpt

BACKGROUND: The intercellular adhesion molecule-1 (ICAM-1) mediates the interaction of activated endothelial cells with leukocytes and plays a fundamental role in the pathogenesis of coronary atherosclerosis. ICAM-1 single-base C/T polymorphism, which determines an amino acid substitution in the ICAM-1 protein in exon 6 codon 469, has been described. Our purpose was to determine whether this C/T polymorphism...

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Identifiers

PMID: 12127369
DOI: 10.1016/s0167-5273(02)00138-9

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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