Article
Bayesian latent trait modeling of migraine symptom data.
Human genetics - 1 Aug 2009
Chen Carla Chia Ming, Keith Jonathan M, Nyholt Dale R, Martin Nicholas G, Mengersen Kerrie L
Abstract excerpt
Definition of disease phenotype is a necessary preliminary to research into genetic causes of a complex disease. Clinical diagnosis of migraine is currently based on diagnostic criteria developed by the International Headache Society. Previously, we examined the natural clustering of these diagnostic symptoms using latent class analysis (LCA) and found that a four-class model was preferred. However, the classes...
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