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Article

Genetic diversity and lack of artemisinin selection signature on the Plasmodium falciparum ATP6 in the Greater Mekong Subregion.

PloS one - 1 Jan 2013

Miao Miao, Wang Zenglei, Yang Zhaoqing, Yuan Lili, Parker Daniel M, Putaporntip Chaturong, Jongwutiwes Somchai, Xangsayarath Phonepadith, Pongvongsa Tiengkham, Moji Hazuhiko, Dinh Tuong Trinh, Abe Tomoko, Nakazawa Shusuke, Kyaw Myat Phone, Yan Guiyun, Sirichaisinthop Jeeraphat, Sattabongkot Jetsumon, Mu Jianbing, Su Xin-zhuan, Kaneko Osamu, Cui Liwang

Abstract excerpt

The recent detection of clinical Artemisinin (ART) resistance manifested as delayed parasite clearance in the Cambodia-Thailand border area raises a serious concern. The mechanism of ART resistance is not clear; but the P. falciparum sarco/endoplasmic reticulum Ca(2+)-ATPase (PfSERCA or PfATP6) has been speculated to be the target of ARTs and thus a potential marker for ART resistance. Here we amplified and...

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Identifiers

PMID: 23555629
DOI: 10.1371/journal.pone.0059192
PMCID: PMC3608609

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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