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Article

Oxidant resistance in a yeast mutant deficient in the Sit4 phosphatase.

Current genetics - 1 May 2008

López-Mirabal H Reynaldo, Winther Jakob R, Kielland-Brandt Morten C

Abstract excerpt

Resistance to thiol oxidation can arise from mutations altering redox homeostasis. A Saccharomyces cerevisiae sit4-110 mutant is here described, which was isolated as resistant to the thiol-specific oxidant dipyridyl disulfide (DPS) and which contains a single-residue substitution in the SIT4 gene. Sit4p is a protein phosphatase with multiple roles in signal transduction through the target-of-rapamycin (TOR)...

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PMID: 18357452
DOI: 10.1007/s00294-008-0184-z

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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