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Article

ATP-dependent activation of p21WAF1/CIP1-associated Cdk2 by Cdc6.

Proceedings of the National Academy of Sciences of the United States of America - 25 Mar 2008

Kan Qiuming, Jinno Shigeki, Yamamoto Hanako, Kobayashi Kohei, Okayama Hiroto

Abstract excerpt

When cells progressing in mid-S phase are damaged with a base-modifying chemical, they arrest in S phase long after the CHK1 checkpoint signal fades out, partly because of p53-mediated long-lasting induction of the cyclin-dependent kinase inhibitor p21(WAF1/CIP1). We have recently found that enfo...

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Source

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Identifiers

PMID: 18356301
DOI: 10.1073/pnas.0706392105
PMCID: PMC2290776

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-18356301-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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